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Drebrin 1 Antibody (DBN-N-03) [Janelia Fluor® 585]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22344JF585

Novus Biologicals, part of Bio-Techne
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NBP2-22344JF585
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Key Product Details

Species Reactivity

Validated:

Human

Applications

CyTOF-ready, Flow (Intracellular), Flow Cytometry, Western Blot

Label

Janelia Fluor 585

Antibody Source

Monoclonal Mouse IgG2B Clone # DBN-N-03

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Drebrin 1 Antibody (DBN-N-03) [Janelia Fluor® 585]

Immunogen

Bacterially expressed N-terminal fragment of recombinant human Drebrin Antibody (DBN-N-03)

Specificity

The mouse monoclonal Drebrin Antibody (DBN-N-03) recognizes drebrin, an approximately 100-125 kDa regulator of actin cytoskeleton.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Drebrin 1 Antibody (DBN-N-03) [Janelia Fluor® 585]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow (Intracellular)

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Drebrin 1

Drebrins are actin-binding proteins, that are developmentally regulated in the process of neuronal growth. Three isoforms, E1 and E2 (embryonic) and A (adult) are generated by alternative RNA splicing from a single debrin gene in the chicken brain. The expression pattern of each isoform is regulated spatially and temporally in the developing brain. It has been suggested that debrin is one of the intracellular regulators of the neuronal morphogenesis (4). Debrin has also been detected in other kinds of non-neuronal human and bovine tissue but its exact role is unknown.

Alternate Names

D0S117E, DBN1, Drba, Drebrin A, Drebrin E, Drebrin E2

Gene Symbol

DBN1

Additional Drebrin 1 Products

Product Documents for Drebrin 1 Antibody (DBN-N-03) [Janelia Fluor® 585]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Drebrin 1 Antibody (DBN-N-03) [Janelia Fluor® 585]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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