Key Product Details

Species Reactivity

Mouse

Applications

ELISA Capture (Matched Antibody Pair), ELISA Detection (Matched Antibody Pair), ELISA Standard (Matched Pair), Immunocytochemistry, Western Blot

Label

Janelia Fluor 646

Antibody Source

Recombinant Monoclonal Rat IgG1 Clone # 109646

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Tyro3/Dtk Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Tyro3/Dtk
Ala31-Ser418
Accession # P55144

Reactivity Notes

0

Specificity

Detects mouse Tyro3/Dtk extracellular domain in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Tyro3/Dtk, recombinant mouse (rm) Mer, or rmAxl is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Applications for Dtk/TYRO3 Antibody (109646) [Janelia Fluor® 646]

Application
Recommended Usage

ELISA Capture (Matched Antibody Pair)

Optimal dilutions of this antibody should be experimentally determined.

ELISA Detection (Matched Antibody Pair)

Optimal dilutions of this antibody should be experimentally determined.

ELISA Standard (Matched Pair)

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Tyro3/Dtk

Receptor protein tyrosine kinases (RPTKs) are a class of transmembrane signaling molecules. They have been shown to regulate signaling cascades that control synaptic function in the central nervous system (CNS). Tyro3 is one of three RPTKs belonging to the Axl/UFO subfamily, that also includes Axl and Mer. Tyro3 is the most commonly expressed of these receptors in the CNS. It may be involved in the cell adhesion process, and is commonly found in adult tissues with expression mostly in brain, testis, vascular and lymphatic tissue.

Long Name

Tyrosine Protein Kinase Receptor TYRO3

Alternate Names

Brt, Dtk, Rse, Sky

Gene Symbol

TYRO3

Additional Tyro3/Dtk Products

Product Documents for Dtk/TYRO3 Antibody (109646) [Janelia Fluor® 646]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Dtk/TYRO3 Antibody (109646) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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