DUSP10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16235

Novus Biologicals, part of Bio-Techne
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NBP2-16235
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DUSP10 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human DUSP10. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (84%).

Localization

Cytoplasm; Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DUSP10 Antibody

Western Blot: DUSP10 Antibody [NBP2-16235]

Western Blot: DUSP10 Antibody [NBP2-16235]

Western Blot: DUSP10 Antibody [NBP2-16235] - Sample (30 ug of whole cell lysate) A: Hela B: HCT11610% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: DUSP10 Antibody [NBP2-16235]

Immunocytochemistry/ Immunofluorescence: DUSP10 Antibody [NBP2-16235]

Immunocytochemistry/Immunofluorescence: DUSP10 Antibody [NBP2-16235] - Analysis of paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: DUSP10 Antibody [NBP2-16235]

Immunohistochemistry-Paraffin: DUSP10 Antibody [NBP2-16235]

Immunohistochemistry-Paraffin: DUSP10 Antibody [NBP2-16235] - U87 xenograft, using DUSP10 antibody at 1:100 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for DUSP10 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DUSP10

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

dual specificity phosphatase 10, dual specificity phosphatase MKP-5, EC 3.1.3.16, EC 3.1.3.48, MAP kinase phosphatase 5, Mitogen-activated protein kinase phosphatase 5, MKP-5dual specificity protein phosphatase 10, MKP5serine/threonine specific protein phosphatase

Gene Symbol

DUSP10

UniProt

Q9Y6W6 (Human)

Additional DUSP10 Products

Product Documents for DUSP10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DUSP10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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