DUSP14 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81046

Novus Biologicals, part of Bio-Techne
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NBP1-81046
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DUSP14 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DUSP14 Antibody

Western Blot: DUSP14 Antibody [NBP1-81046]

Western Blot: DUSP14 Antibody [NBP1-81046]

Western Blot: DUSP14 Antibody [NBP1-81046] - Analysis in control (vector only transfected HEK293T lysate) and DUSP14 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: DUSP14 Antibody [NBP1-81046]

Immunocytochemistry/ Immunofluorescence: DUSP14 Antibody [NBP1-81046]

Immunocytochemistry/Immunofluorescence: DUSP14 Antibody [NBP1-81046] - Staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: DUSP14 Antibody [NBP1-81046]

Immunohistochemistry-Paraffin: DUSP14 Antibody [NBP1-81046]

Immunohistochemistry-Paraffin: DUSP14 Antibody [NBP1-81046] - Staining of human small intestine shows strong cytoplasmic and membranous positivity in glandular cells.
View 3 more images

Applications for DUSP14 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DUSP14

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-basedprotein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosineand serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP(mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009(PubMed 19228121)).(supplied by OMIM)

Alternate Names

dual specificity phosphatase 14, EC 3.1.3.16, EC 3.1.3.48, MAP kinase phosphatase 6, Mitogen-activated protein kinase phosphatase 6, MKP-1 like protein tyrosine phosphatase, MKP-1-like protein tyrosine phosphatase, MKP-6, MKP6MKP-Ldual specificity protein phosphatase 14

Entrez Gene IDs

11072 (Human)

Gene Symbol

DUSP14

UniProt

O95147 (Human)

Additional DUSP14 Products

Product Documents for DUSP14 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DUSP14 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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