DUSP4 Antibody (1D12)

Novus Biologicals, part of Bio-Techne | Catalog # H00001846-M08

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Kappa Clone # 1D12

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DUSP4 Antibodies »

Product Specifications

Immunogen

DUSP4 (AAH02671, 1 a.a. ~ 394 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC

Specificity

DUSP4 (1D12)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3 Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for DUSP4 Antibody (1D12)

Western Blot: DUSP4 Antibody (1D12) [H00001846-M08]

Western Blot: DUSP4 Antibody (1D12) [H00001846-M08]

Western Blot: DUSP4 Antibody (1D12) [H00001846-M08] - Analysis of DUSP4 expression in transfected 293T cell line by DUSP4 monoclonal antibody (M08), clone 1D12. Lane 1: DUSP4 transfected lysatE (43 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: DUSP4 Antibody (1D12) [H00001846-M08]

Immunocytochemistry/ Immunofluorescence: DUSP4 Antibody (1D12) [H00001846-M08]

Immunocytochemistry/Immunofluorescence: DUSP4 Antibody (1D12) [H00001846-M08] - Analysis of monoclonal antibody to DUSP4 on HeLa cell. Antibody concentration 10 ug/ml
ELISA: DUSP4 Antibody (1D12) [H00001846-M08]

ELISA: DUSP4 Antibody (1D12) [H00001846-M08]

ELISA: DUSP4 Antibody (1D12) [H00001846-M08] - Detection limit for recombinant GST tagged DUSP4 is approximately 3ng/ml as a capture antibody.

Applications for DUSP4 Antibody (1D12)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DUSP4

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

Alternate Names

dual specificity phosphatase 4, Dual specificity protein phosphatase hVH2, EC 3.1.3.16, EC 3.1.3.48, HVH2serine/threonine specific protein phosphatase, MAP kinase phosphatase 2, Mitogen-activated protein kinase phosphatase 2, MKP-2dual specificity protein phosphatase 4, MKP2VH1 homologous phosphatase 2, TYP, VH2

Entrez Gene IDs

1846 (Human)

Gene Symbol

DUSP4

OMIM

602747 (Human)

UniProt

AAH02671 (Human)

Additional DUSP4 Products

Product Documents for DUSP4 Antibody (1D12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DUSP4 Antibody (1D12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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