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Dynamin 3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56017

Novus Biologicals, part of Bio-Techne
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NBP2-56017
NBP2-56017-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: QQRSSQVHKKTTVGNQGTNLPPSRQIVIRKG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Dynamin 3 Antibody

Immunocytochemistry/ Immunofluorescence: Dynamin 3 Antibody [NBP2-56017]

Immunocytochemistry/ Immunofluorescence: Dynamin 3 Antibody [NBP2-56017]

Immunocytochemistry/Immunofluorescence: Dynamin 3 Antibody [NBP2-56017] - Staining of human cell line U-251 MG shows localization to the Golgi apparatus.

Applications for Dynamin 3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dynamin 3

The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin 1 is expressed exclusively in neurons, Dynamin 2 is ubiquitously expressed, and Dynamin 3 is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.

Alternate Names

Dyna III, dynamin 3, dynamin family member, dynamin-3, EC 3.6.5.5, MGC70433, T-dynamin, testicular

Gene Symbol

DNM3

Additional Dynamin 3 Products

Product Documents for Dynamin 3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dynamin 3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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