Dystonin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-35915

Novus Biologicals, part of Bio-Techne
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NBP3-35915-100ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Dystonin Antibodies »

Product Summary for Dystonin Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human Dystonin (NP_001714.1).

Sequence:
MHSSSYSYRSSDSVFSNTTSTRTSLDSNENLLLVHCGPTLINSCISFGSESFDGHRLEMLQQIANRVQRDSVICEDKLILAGNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHVIDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSKGRILTTEQTKLMISGITQSLNSGFAQTLHPSLTSGLTQSLTPSLTSSSMTSGLSSGMTSRLTPSVTPAYTPGFPSGLVPNFSSGVEPNSLQTLKLMQIRKPLLKSSLLDQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

861 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications for Dystonin Antibody

Application
Recommended Usage

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Preservative

0.01% Thimerosal

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Dystonin

Dystonin encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been known that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.

Alternate Names

230 kDa bullous pemphigoid antigen, BP240, BPAFLJ30627, BPAG1FLJ32235, Bullous pemphigoid antigen, Bullous pemphigoid antigen 1, bullous pemphigoid antigen 1, 230/240kDa, CATX-15, D6S1101, DKFZp564B2416, DMHCATX15, DT, Dystonia musculorum protein, dystonin, FLJ13425, FLJ21489, FLJ46791, Hemidesmosomal plaque protein, KIAA0465, KIAA0728, KIAA1470, MACF2, trabeculin-beta

Gene Symbol

DST

Additional Dystonin Products

Product Documents for Dystonin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Dystonin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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