DZIP3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58053

Novus Biologicals, part of Bio-Techne
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NBP2-58053
NBP2-58053-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DZIP3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: ESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNLESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DZIP3 Antibody

Immunocytochemistry/ Immunofluorescence: DZIP3 Antibody [NBP2-58053]

Immunocytochemistry/ Immunofluorescence: DZIP3 Antibody [NBP2-58053]

Immunocytochemistry/Immunofluorescence: DZIP3 Antibody [NBP2-58053] - Staining of human cell line U-2 OS shows localization to vesicles.

Applications for DZIP3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DZIP3

The DZIP3 gene codes a E3 ubiquitin-protein ligase DZIP3 protein that in one isoform is 1,208 amino acids long and 138 kDA and in the other is 303 amino acids long at 35 kDA. These proteins are able to specifically bind RNA as well as control ubiquitination and proteasomal degradation of target proteins by receiving ubiquitin from an E2 ubiquitin-conjugating enzyme (in the form of a thioester) then transfers the material to targeted substrates. DZIP3 is active in adaptive immune system, protein modification, and antigen processing (specifically ubiquitination and proteasome degradation as described above). DZIP3 has been researched in various diseases such as azoospermia and ataxia.

Alternate Names

DAZ interacting protein 3, zinc finger, DAZ-interacting protein 3, E3 ubiquitin-protein ligase DZIP3, EC 6.3.2.-, FLJ13327, FLJ57977, FLJ58022, FLJ58223, hRUL138KIAA0675, human RNA-binding ubiquitin ligase of 138 kDa, RNA-binding ubiquitin ligase of 138 kDa, UURF2, UURF2 ubiquitin ligase, zinc finger DAZ interacting protein 3

Gene Symbol

DZIP3

Additional DZIP3 Products

Product Documents for DZIP3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DZIP3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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