E2F3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81745

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all E2F3 Antibodies »

Product Specifications

Immunogen

E2F3 antibody was raised against a 15 amino acid peptide near the center of human E2F3. The immunogen is located within amino acids 150 - 200 of E2F3. Amino Acid Squence: PDSPKTPKSPSEKT

Specificity

E2F3 antibody is human and mouse reactive. At least three isoforms of E2F3 are known to exist; this antibody will detect only the largest isoform. This antibody is predicted to not cross-react with other members of the E2F transcription factor family.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for E2F3 Antibody - BSA Free

Western Blot: E2F3 AntibodyBSA Free [NBP2-81745]

Western Blot: E2F3 AntibodyBSA Free [NBP2-81745]

Western Blot: E2F3 Antibody [NBP2-81745] - Western blot analysis of E2F3 in human lymph node tissue lysate with E2F3 antibody at 1 ug/ml.
Immunocytochemistry/ Immunofluorescence: E2F3 Antibody - BSA Free [NBP2-81745]

Immunocytochemistry/ Immunofluorescence: E2F3 Antibody - BSA Free [NBP2-81745]

Immunocytochemistry/Immunofluorescence: E2F3 Antibody [NBP2-81745] - Immunofluorescence of E2F3 in human lymph node tissue with E2F3 antibody at 20 ug/ml.
Immunohistochemistry: E2F3 Antibody - BSA Free [NBP2-81745]

Immunohistochemistry: E2F3 Antibody - BSA Free [NBP2-81745]

Immunohistochemistry: E2F3 Antibody [NBP2-81745] - Immunohistochemistry of E2F3 in human lymph node tissue with E2F3 antibody at 5 ug/ml.
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Applications for E2F3 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: E2F3

E2F3 is encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.

Alternate Names

DKFZp686C18211, E2F transcription factor 3, E2F-3, KIAA0075, MGC104598, transcription factor E2F3

Gene Symbol

E2F3

Additional E2F3 Products

Product Documents for E2F3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for E2F3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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