EBI2/GPR183 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27352

Novus Biologicals, part of Bio-Techne
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NBP2-27352
NBP2-27352SS
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Key Product Details

Species Reactivity

Human, Monkey, Primate

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all EBI2 Antibodies »

Product Specifications

Immunogen

A portion of amino acids 300-350 of human EBI2 was used as the immunogen.

Reactivity Notes

Chimpanzee (100%), Mouse, Rat (93%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for EBI2/GPR183 Antibody

Western Blot: EBI2/GPR183 Antibody [NBP2-27352]

Western Blot: EBI2/GPR183 Antibody [NBP2-27352]

Western Blot: EBI2/GPR183 Antibody [NBP2-27352] - Analysis of EBI2 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, and 3) rat brain lysate using this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Immunohistochemistry-Paraffin: EBI2/GPR183 Antibody [NBP2-27352]

Immunohistochemistry-Paraffin: EBI2/GPR183 Antibody [NBP2-27352]

Immunohistochemistry-Paraffin: EBI2/GPR183 Antibody [NBP2-27352] - Analysis of EBI2 in human stomach tumor tissue using an isotype control (top left) and this antibody (bottom left, right) at 5 ug/ml.

Applications for EBI2/GPR183 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5ug/ml

Western Blot

2-4ug/ml~

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: EBI2

G-protein coupled receptor 183 (EBI2) belongs to the G-protein coupled receptor 1 family of proteins. It is an orphan seven-transmembrane receptor originally identified as most up-regulated gene (>200-fold) in EBV-infected cells. It plays a central role during humoral immunity. It promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses. It is expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. It is also reported to be highly expressed in lung, heart and gastrointestinal tract. EBI2 deficiency in mice led to a reduction in the early antibody response to a T-dependent antigen.

Long Name

Epstein-Barr Virus Induced Gene 2

Alternate Names

GPR183

Gene Symbol

GPR183

UniProt

P32249

Additional EBI2 Products

Product Documents for EBI2/GPR183 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for EBI2/GPR183 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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