EDA/Ectodysplasin Antibody (MM0254-3T2) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12270

Novus Biologicals, part of Bio-Techne
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NBP2-12270
NBP2-12270-0.025mg
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MM0254-3T2

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all EDA/Ectodysplasin Antibodies »

Product Summary for EDA/Ectodysplasin Antibody (MM0254-3T2) - Azide and BSA Free

Immunogen

Human recombinant EDA/Ectodysplasin (extracellular domain)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for EDA/Ectodysplasin Antibody (MM0254-3T2) - Azide and BSA Free

Immunohistochemistry-Paraffin: EDA/Ectodysplasin Antibody (MM0254-3T2) - Azide and BSA Free [NBP2-12270]

Immunohistochemistry-Paraffin: EDA/Ectodysplasin Antibody (MM0254-3T2) - Azide and BSA Free [NBP2-12270]

Immunohistochemistry-Paraffin: EDA/Ectodysplasin Antibody (MM0254-3T2) [NBP2-12270] - 10% Buffer formalin fixed and parffine embedded human placetal tissue section (4um) is subjected IHC staining using NBP2-12270. Tissue section was pretreated in citric buffer (pH 6.0) with microwave for antige retrieval before IHC is applied.

Applications for EDA/Ectodysplasin Antibody (MM0254-3T2) - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EDA/Ectodysplasin

Ectodysplasin (EDA) is a type II transmembrane protein belonging to the TNF superfamily. It can be expressed as eight alternatively spliced isoforms that are encoded by the EDA gene. Isoforms of EDA are expressed in cells of ectodermal origin, where they are localized to the cell surface and can be released in a soluble form following cleavage by Furin. The EDA-A1 and EDA-A2 splice variants differ by the deletion of two amino acids in the extracellular domain of EDA-A2. Despite this minor difference, EDA-A1 and EDA-A2 display strong receptor specificity. EDA-A1 binds to EDAR, whereas EDA-A2 binds to XEDAR. EDA-A1 and EDA-A2 are required during development, and loss or mutation of EDA results in abnormal development of hair follicles, sweat glands, and teeth. Mutations in the EDA gene are associated with a group of developmental disorders identified as ectodermal dysplasia type 1.

Alternate Names

Tabby, XHED, XLHED

Gene Symbol

EDA

UniProt

NP_001005609

Additional EDA/Ectodysplasin Products

Product Documents for EDA/Ectodysplasin Antibody (MM0254-3T2) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for EDA/Ectodysplasin Antibody (MM0254-3T2) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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