EIF2B2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38572

Novus Biologicals, part of Bio-Techne
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NBP2-38572
NBP2-38572-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all EIF2B2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: RETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for EIF2B2 Antibody

Immunohistochemistry-Paraffin: EIF2B2 Antibody [NBP2-38572]

Immunohistochemistry-Paraffin: EIF2B2 Antibody [NBP2-38572]

Immunohistochemistry-Paraffin: EIF2B2 Antibody [NBP2-38572] - Staining in human thyroid gland and liver tissues using anti-EIF2B2 antibody. Corresponding EIF2B2 RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: EIF2B2 Antibody [NBP2-38572]

Immunocytochemistry/ Immunofluorescence: EIF2B2 Antibody [NBP2-38572]

Immunocytochemistry/Immunofluorescence: EIF2B2 Antibody [NBP2-38572] - Staining of human cell line MCF7 shows localization to nucleoplasm, plasma membrane & focal adhesion sites. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: EIF2B2 Antibody [NBP2-38572]

Immunohistochemistry-Paraffin: EIF2B2 Antibody [NBP2-38572]

Immunohistochemistry-Paraffin: EIF2B2 Antibody [NBP2-38572] - Staining of human liver shows low expression as expected.
View 1 more images

Applications for EIF2B2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EIF2B2

Eukaryotic initiation factor-2B (EIF2B) is a GTP exchange protein essential for protein synthesis. It consists of alpha (EIF2B1; MIM 606686), beta (EIF2B2), gamma (EIF2B3; MIM 606273), delta (EIF2B4; MIM 606687), and epsilon (EIF2B5; MIM 603945) subunits. EIF2B activates its EIF2 (see MIM 603907) substrate by exchanging EIF2-bound GDP for GTP.[supplied by OMIM]

Alternate Names

EIF2B, eIF-2B GDP-GTP exchange factor subunit beta, EIF2BB, EIF-2Bbeta, eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD), eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa, S20I15, S20III15, translation initiation factor eIF-2B subunit beta

Gene Symbol

EIF2B2

UniProt

P49770 (Human)

Additional EIF2B2 Products

Product Documents for EIF2B2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for EIF2B2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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