EIF3G Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24685

Novus Biologicals, part of Bio-Techne
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NBP2-24685
NBP2-24685SS
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Key Product Details

Species Reactivity

Validated:

Human, Primate

Predicted:

Bovine (92%), Canine (92%), Chimpanzee (100%), Equine (92%), Feline (92%), Porcine (92%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all EIF3G Antibodies »

Product Summary for EIF3G Antibody

Immunogen

A portion of amino acids 50-100 of human eIF3G was used as the immunogen.

Reactivity Notes

The amino acid sequence used as immunogen is 84% homologous in mouse.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for EIF3G Antibody

Western Blot: EIF3G Antibody [NBP2-24685]

Western Blot: EIF3G Antibody [NBP2-24685]

Western Blot: EIF3G Antibody [NBP2-24685] - analysis of eIF3G isoforms in 1) Hela cell lysate and 2) RAW cell lysate using this antibody. 0 ug/ml.
Immunohistochemistry-Paraffin: EIF3G Antibody [NBP2-24685]

Immunohistochemistry-Paraffin: EIF3G Antibody [NBP2-24685]

Immunohistochemistry-Paraffin: EIF3G Antibody [NBP2-24685] - analysis of eIF3G in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top left) and this antibody (bottom left, right) at 5 ug/ml.

Applications for EIF3G Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

4.0-5.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EIF3G

Eukaryotic initiation factor 3 subunit G (eIF3G) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5'-end of cellular mRNAs near the cap structure (m7GpppN). eIF3G has been shown to directly interact with AIF (apoptosis inducing factor), a protein that plays a role in caspase-independent apoptosis. AIF is able to inhibit protein synthesis via its interaction with eIF3g.

Alternate Names

eIF3 p42, eIF3 p44, eIF-3-delta, eIF3-delta, eIF3g, EIF3-P42, eIF3-p44, EIF3S4eIF-3 RNA-binding subunit, Eukaryotic translation initiation factor 3 RNA-binding subunit, Eukaryotic translation initiation factor 3 subunit 4, eukaryotic translation initiation factor 3 subunit G, eukaryotic translation initiation factor 3 subunit p42, eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD), eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa, eukaryotic translation initiation factor 3, subunit G

Gene Symbol

EIF3G

UniProt

O75821 (Human)

Additional EIF3G Products

Product Documents for EIF3G Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for EIF3G Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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