ELAC2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00060528-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ELAC2 Antibodies »

Product Specifications

Immunogen

ELAC2 (NP_060597.3, 1 a.a. - 826 a.a.) full-length human protein. MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIELAVRPHSAPEYEDETMTVYQIPIHSEQRRGKHQPWQSPERPLSRLSPERSSDSELNENEPHLPHGVSQRRGVRDSSLVVAFICKLHLKRGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHEGREILAEELCTPPDPGAAFVVVECPDESFIQPICENATFQRYQGKADAPVALVVHMAPASVLVDSRYQQWMERFGPDTQHLVLNENCASVHNLRSHKIQTQLNLIHPDIFPLLTSFRCKKEGPTLSVPMVQGECLLKYQLRPRREWQRDAIITCNPEEFIVEALQLPNFQQSVQEYRRSAQDGPAPAEKRSQYPEIIFLGTGSAIPMKIRNVSATLVNISPDTSLLLDCGEGTFGQLCRHYGDQVDRVLGTLAAVFVSHLHADHHTGLPSILLQRERALASLGKPLHPLLVVAPNQLKAWLQQYHNQCQEVLHHISMIPAKCLQEGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGCALVHTSGWKVVYSGDTMPCEALVRMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAISVGMRMNAEFIMLNHFSQRYAKVPLFSPNFSEKVGVAFDHMKVCFGDFPTMPKLIPPLKALFAGDIEEMEERREKRELRQVRAALLSRELAGGLEDGEPQQKRAHTEEPQAKKVRAQ

Specificity

Reacts with elaC homolog 2 (E. coli).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ELAC2 Antibody

Western Blot: ELAC2 Antibody [H00060528-D01P]

Western Blot: ELAC2 Antibody [H00060528-D01P]

Western Blot: ELAC2 Antibody [H00060528-D01P] - Analysis of ELAC2 expression in human liver.
Western Blot: ELAC2 Antibody [H00060528-D01P]

Western Blot: ELAC2 Antibody [H00060528-D01P]

Western Blot: ELAC2 Antibody [H00060528-D01P] - Analysis of ELAC2 expression in transfected 293T cell line by ELAC2 polyclonal antibody.Lane 1: ELAC2 transfected lysate(92.20 KDa).Lane 2: Non-transfected lysate.

Applications for ELAC2 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against tissue and transfected lysate in western blot, and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ELAC2

The protein encoded by the ELAC2 gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity,which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activatedSmad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expressioncan suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased riskof prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. (providedby RefSeq)

Alternate Names

EC 3.1.26.11, elaC homolog 2 (E. coli), ElaC homolog protein 2, ELC2, FLJ10530, FLJ36693, FLJ42848, Heredity prostate cancer protein 2, HPC2elaC (E. coli) homolog 2, putative prostate cancer susceptibility protein HPC2/ELAC2, Ribonuclease Z 2, RNase Z 2, tRNA 3 endonuclease 2, tRNase Z (long form), tRNase Z 2, zinc phosphodiesterase ELAC protein 2

Entrez Gene IDs

60528 (Human)

Gene Symbol

ELAC2

UniProt

NP_060597.3 (Human)

Additional ELAC2 Products

Product Documents for ELAC2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ELAC2 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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