EMAP-II/AIMP1 Antibody (S01-5A9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19624

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19624-100ul
NBP3-19624-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S01-5A9

Concentration

0.3 mg/ml

View all EMAP-II Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human EMAP-II/AIMP1 (Uniprot # Q12904)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

34 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for EMAP-II/AIMP1 Antibody (S01-5A9)

Western Blot: EMAP-II/AIMP1 Antibody (S01-5A9) [NBP3-19624]

Western Blot: EMAP-II/AIMP1 Antibody (S01-5A9) [NBP3-19624]

Western Blot: EMAP-II/AIMP1 Antibody (S01-5A9) [NBP3-19624] - Western blot detection of EMAP-II/AIMP1 in C6 cell lysates using NBP3-19624 (1:1000 diluted). Predicted band size: 34kDa. Observed band size: 34kDa.

Applications for EMAP-II/AIMP1 Antibody (S01-5A9)

Application
Recommended Usage

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EMAP-II

EMAP II (Endothelial-Monocyte-Activating Polypeptide II) is a proinflammatory cytokine and chemoattractant of macrophages and polymorphonuclear lymphocytes. EMAP II is synthesized as a 34 kDa precursor molecule which is cleaved to a biologically active 22 kDa mature polypeptide. This active protein is known to induce the procoagulant protein tissue factor on the surface of endothelial cells and modulate other properties of endothelial cells and monocytes in vitro, including the stimulation of TNF-alpha and myeloperoxidase. EMAP II activates neutrophils in vivo and induces an inflammatory reaction and tumor regression. EMAP II induces apoptosis in proliferating endothelial cells and inhibits neovascularization. This anti-angiogenic property is of interest to tumor biology. EMAP II is also a negative modulator of lung vascular growth.

Long Name

Endothelial-Monocyte Activating Polypeptide II

Alternate Names

AIMP1, EMAPII, SCYE1

Gene Symbol

AIMP1

Additional EMAP-II Products

Product Documents for EMAP-II/AIMP1 Antibody (S01-5A9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for EMAP-II/AIMP1 Antibody (S01-5A9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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