Endothelin-3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00001908-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Endothelin-3 Antibodies »

Product Specifications

Immunogen

EDN3 (NP_000105.1, 1 a.a. - 238 a.a.) full-length human protein. MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP

Specificity

EDN3 - endothelin 3,

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Endothelin-3 Antibody

Western Blot: Endothelin-3 Antibody [H00001908-D01P]

Western Blot: Endothelin-3 Antibody [H00001908-D01P]

Western Blot: Endothelin-3 Antibody [H00001908-D01P] - Analysis of EDN3 expression in human placenta.
Western Blot: Endothelin-3 Antibody [H00001908-D01P]

Western Blot: Endothelin-3 Antibody [H00001908-D01P]

Western Blot: Endothelin-3 Antibody [H00001908-D01P] - Analysis of EDN3 expression in transfected 293T cell line by EDN3 polyclonal antibody.Lane 1: EDN3 transfected lysate(25.50 KDa).Lane 2: Non-transfected lysate.

Applications for Endothelin-3 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Endothelin-3

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq]

Alternate Names

EDN3, Endothelin3

Entrez Gene IDs

1908 (Human)

Gene Symbol

EDN3

UniProt

NP_000105.1 (Human)

Additional Endothelin-3 Products

Product Documents for Endothelin-3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Endothelin-3 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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