ERCC6L Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00054821-D01P

Novus Biologicals, part of Bio-Techne
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H00054821-D01P
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ERCC6L Antibodies »

Product Specifications

Immunogen

ERCC6L (AAH08808.1, 1 a.a. - 419 a.a.) full-length human protein. MEKSFATKNEAVQKETLQEGPKQEALQEDPLESFNYVLSKSTKADIGPNLDQLKDDEILRHCNPWPIISITNESQNAESNVSIIEIADDLSASHSALQDAQASEAKLEEEPSASSPQYACDFNLFLEDSADNRQNFSSQSLEHVEKENSLCGSAPNSRAGFVHSKTCLSWEFSEKDDEPEEVVVKAKIRSKARRIVSDGEDEDDSFKDTSSINPFNTSLFQFSSVKQFDASTPKNDISPPGRFFSSQIPSSVNKSMNSRRSLASRRSLINMVLDHVEDMEERLDDSSEAKGPEDYPEEGVEESSGEASKYTEEDPSGETLSSENKSSWLMTSKPSALAQETSLGAPEPLSGEQLVGSPQDKAAEATNDYETLVKRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

Specificity

ERCC6L - excision repair cross-complementing rodent repair deficiency, complementation group 6-like,

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ERCC6L Antibody

Western Blot: ERCC6L Antibody [H00054821-D01P]

Western Blot: ERCC6L Antibody [H00054821-D01P]

Western Blot: ERCC6L Antibody [H00054821-D01P] - Analysis of ERCC6L expression in human colon.
Immunocytochemistry/ Immunofluorescence: ERCC6L Antibody [H00054821-D01P]

Immunocytochemistry/ Immunofluorescence: ERCC6L Antibody [H00054821-D01P]

Immunocytochemistry/Immunofluorescence: ERCC6L Antibody [H00054821-D01P] - IF analysis of ERCC6L in mouse and human cell lines. Image courtesy of product review submitted by Corentin Laulier.
Western Blot: ERCC6L Antibody [H00054821-D01P]

Western Blot: ERCC6L Antibody [H00054821-D01P]

Western Blot: ERCC6L Antibody [H00054821-D01P] - Analysis of ERCC6L expression in transfected 293T cell line by ERCC6L polyclonal antibody.Lane 1: ERCC6L transfected lysate(46.20 KDa).Lane 2: Non-transfected lysate.

Applications for ERCC6L Antibody

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. This antibody may also be useful in Immunofluorescence, as per a customer product review. Immunocytochemistry/Immunofluorescence was reported in scientific literature. Use in Immunohistochemistry reported in scientific literature (PMID 24589582)

Reviewed Applications

Read 1 review rated 5 using H00054821-D01P in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ERCC6L

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase

Alternate Names

ATP-dependent helicase ERCC6-like, DNA excision repair protein ERCC-6-like, EC 3.6.1, EC 3.6.4.12, excision repair cross-complementing rodent repair deficiency, complementationgroup 6-like, excision repair protein ERCC6-like, FLJ20105, MGC131695, PICHexcision repair cross-complementing rodent repair deficiency complementationgroup 6 - like, PLK1-interacting checkpoint helicase, SNF2/RAD54 family protein, Tumor antigen BJ-HCC-15

Entrez Gene IDs

54821 (Human)

Gene Symbol

ERCC6L

UniProt

AAH08808.1 (Human)

Additional ERCC6L Products

Product Documents for ERCC6L Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ERCC6L Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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