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ERCC8 Antibody (PSH0-87)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-32316

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-32316

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # PSH0-87

Concentration

1 mg/ml

Product Specifications

Immunogen

Recombinant protein within human ERCC8 aa 1-396 / 396. (Uniprot: Q13216)

Localization

Nucleus, Nucleus matrix.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ERCC8 Antibody (PSH0-87)

ERCC8 Antibody (PSH0-87)

Western Blot: ERCC8 Antibody (PSH0-87) [NBP3-32316]

Western Blot: ERCC8 Antibody (PSH0-87) [NBP3-32316] - Western blot analysis of ERCC8 on different lysates with Rabbit anti-ERCC8 antibody (NBP3-32316) at 1/1,000 dilution.

Lane 1: 293T cell lysate
Lane 2: SH-SY5Y cell lysate
Lane 3: HepG2 cell lysate

Lysates/proteins at 30 ug/Lane.

Predicted band size: 44 kDa
Observed band size: 55 kDa

Exposure time: 1 minute 32 seconds;

4-20% SDS-PAGE gel.

Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (NBP3-32316) at 1/1,000 dilution was used in 5% NFDM/TBST at 4C overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:100,000 dilution was used for 1 hour at room temperature.

Applications for ERCC8 Antibody (PSH0-87)

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH7.4), 0.1% BSA and 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ERCC8

ERCC8 encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

Alternate Names

CKN1DNA excision repair protein ERCC-8, Cockayne syndrome 1 (classical), Cockayne syndrome WD repeat protein CSA, CSACockayne syndrome WD-repeat protein CSA, excision repair cross-complementing rodent repair deficiency, complementationgroup 8

Gene Symbol

ERCC8

Additional ERCC8 Products

Product Documents for ERCC8 Antibody (PSH0-87)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ERCC8 Antibody (PSH0-87)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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