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ERN2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17487

Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-17487-100ul
NBP3-17487-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for ERN2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: HHELPPVLHTTMLRVHPTLGSGTAETRPPENTQAPAFFLELLSLSREKLWDSELHPEEKTPDSYLGLGPQD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ERN2 Antibody

Immunohistochemistry-Paraffin: ERN2 Antibody [NBP3-17487]

Immunohistochemistry-Paraffin: ERN2 Antibody [NBP3-17487]

Immunohistochemistry-Paraffin: ERN2 Antibody [NBP3-17487] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Applications for ERN2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ERN2

Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins

Alternate Names

EC 2.7.11, endoplasmic reticulum to nucleus signaling 2, endoplasmic reticulum to nucleus signalling 2, Endoplasmic reticulum-to-nucleus signaling 2, ER to nucleus signalling 2, hIRE2p, inositol-requiring 1 beta, Inositol-requiring protein 2, IRE1, S. cerevisiae, homolog of, IRE1-BETA, IRE1bIRE1 beta, IRE2, serine/threonine-protein kinase/endoribonuclease IRE2

Gene Symbol

ERN2

Additional ERN2 Products

Product Documents for ERN2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ERN2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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