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ETV3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-29900

Novus Biologicals, part of Bio-Techne
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NBP3-29900

Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Between 350 and 400

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ETV3 Antibody

ETV3 Antibody

Immunoprecipitation:ETV3 AntibodyNBP3-29900] -

Immunoprecipitation:ETV3 AntibodyNBP3-29900] -Detection of human ETV3 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from Jurkat cells. Antibodies: Affinity purified rabbit anti-ETV3 antibody NBP3-29900 used for IP at 6 µg/mg lysate. ETV3 was also immunoprecipitated by rabbit anti-ETV3., which recognizes a downstream epitope. For blotting immunoprecipitated ETV3, was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Applications for ETV3 Antibody

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ETV3

The ETV3 gene encodes an ETS translocation variant 3 protein, that in isoform 1 is 512 amino acids long at 57 kDA and in isoform 2 is 143 amino acids long at nearly 17 kDA. This protein functions in terminal macrophage differentiation as a transcriptional repressor that contributes to growth arrest. It also represses MMP1 promoter activity and interacts with the MYC and DDX20 genes. ETV3 is linked to diseases heart disease, hypertension, ADHD, and conduct disorder.

Alternate Names

bA110J1.4, ETS domain transcriptional repressor PE1, ETS translocation variant 3, ets variant 3, ets variant gene 3, ETS family transcriptional repressor, METS, Mitogenic Ets transcriptional suppressor, PE-1ets variant gene 3, PE1FLJ79173

Gene Symbol

ETV3

Additional ETV3 Products

Product Documents for ETV3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ETV3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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