ETV6/Tel Antibody (3B10)

Novus Biologicals, part of Bio-Techne | Catalog # H00002120-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3B10

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ETV6 Antibodies »

Product Specifications

Immunogen

ETV6 (AAH43399, 1 a.a. ~ 452 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSETPAQCSIKQERISYTPPESPVPSYASSTPLHVPVPRALRMEEDSIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQRKPRILFSPFFHPGNSIHTQPEVILHQNHEEDNCVQRTPRPSVDNVHHNPPTIELLHRSRSPITTNHRPSPDPEQRPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYPLSVSPMENNHCPASSESHPKPSSPRQESTRVIQLMPSPIMHPLILNPRHSVDFKQSRLSEDGLHREGKPINLSHREDLAYMNHIMVSVSPPEEHAMPIGRIADCRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIMSGRTDRLEHLESQELDEQIYQEDEC

Localization

Nuclear

Specificity

ETV6 - ets variant gene 6 (TEL oncogene)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for ETV6/Tel Antibody (3B10)

Western Blot: ETV6/Tel Antibody (3B10) [H00002120-M01]

Western Blot: ETV6/Tel Antibody (3B10) [H00002120-M01]

Western Blot: ETV6/Tel Antibody (3B10) [H00002120-M01] - ETV6 monoclonal antibody (M01), clone 3B10 Analysis of ETV6 expression in Jurkat.
Immunohistochemistry-Paraffin: ETV6/Tel Antibody (3B10) [H00002120-M01]

Immunohistochemistry-Paraffin: ETV6/Tel Antibody (3B10) [H00002120-M01]

Immunohistochemistry-Paraffin: ETV6/Tel Antibody (3B10) [H00002120-M01] - Analysis of monoclonal antibody to ETV6 on formalin-fixed paraffin-embedded human placenta. Antibody concentration 3 ug/ml.
Sandwich ELISA: ETV6/Tel Antibody (3B10) [H00002120-M01] - Detection limit for recombinant GST tagged ETV6 is approximately 0.1ng/ml as a capture antibody.

Applications for ETV6/Tel Antibody (3B10)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IHC-P and ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ETV6

Tel encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N terminal pointed (PNT) domain that is involved in the protein protein interactions with itself and other proteins, and a C terminal DNA binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Long Name

ETS Translocation Variant 6

Alternate Names

TEL, TEL/ABL

Entrez Gene IDs

2120 (Human)

Gene Symbol

ETV6

OMIM

600618 (Human)

UniProt

AAH43399 (Human)

Additional ETV6 Products

Product Documents for ETV6/Tel Antibody (3B10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ETV6/Tel Antibody (3B10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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