ETV6/Tel Antibody (SR1935)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22355

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22355-100ul
NBP3-22355-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1935

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ETV6 Antibodies »

Product Summary for ETV6/Tel Antibody (SR1935)

Immunogen

A synthesized peptide derived from human ETV6/Tel (Uniprot #: P41212)

Specificity

Detects endogenous levels of total ETV6/Tel

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ETV6/Tel Antibody (SR1935)

Western Blot: ETV6/Tel Antibody (SR1935) [NBP3-22355] -

Western Blot: ETV6/Tel Antibody (SR1935) [NBP3-22355] - Western blot analysis using NBP3-22355 in A431 cell lysate.

Applications for ETV6/Tel Antibody (SR1935)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ETV6

Tel encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N terminal pointed (PNT) domain that is involved in the protein protein interactions with itself and other proteins, and a C terminal DNA binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Long Name

ETS Translocation Variant 6

Alternate Names

TEL, TEL/ABL

Gene Symbol

ETV6

Additional ETV6 Products

Product Documents for ETV6/Tel Antibody (SR1935)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ETV6/Tel Antibody (SR1935)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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