EVER2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76368

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all EVER2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human EVER2. The immunogen is located within amino acids 50 - 100 of EVER2. Amino Acid Squence: WRQWQRRRQTVERRLREA

Specificity

At least two isoforms of EVER2 are known to exist; this antibody will only recognize the larger isoform. EVER2 has no cross-reactivity to EVER1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for EVER2 Antibody - BSA Free

Western Blot: EVER2 AntibodyBSA Free [NBP1-76368]

Western Blot: EVER2 AntibodyBSA Free [NBP1-76368]

Western Blot: EVER2 Antibody [NBP1-76368] - Rat thymus tissue lysate with EVER2 antibody at (A) 1 and (B) 2 ug/ml.

Applications for EVER2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EVER2

Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc. At least two isoforms of EVER2 are known to exist; this antibody will only recognize the larger isoform. EVER2 has no cross-reactivity to EVER1.

Alternate Names

epidermodysplasia verruciformis 2, Epidermodysplasia verruciformis protein 2, EV2, EVER2MGC102701, EVIN2FLJ43684, FLJ40668, MGC40121, transmembrane channel-like 8, transmembrane channel-like protein 8

Gene Symbol

TMC8

UniProt

AAM44454 (Human)

Additional EVER2 Products

Product Documents for EVER2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for EVER2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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