EXOSC3 Antibody (5C3)

Novus Biologicals, part of Bio-Techne | Catalog # H00051010-M03

Novus Biologicals, part of Bio-Techne
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H00051010-M03
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 5C3

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all EXOSC3 Antibodies »

Product Specifications

Immunogen

EXOSC3 (AAH02437, 1 a.a. ~ 275 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAEPASVAAESLAGSRARAARTVLGQVVLPGEELLLPEQEDAEGPGGAVERPLSLNARACSRVRVVCGPGLRRCGDRLLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRLAES

Reactivity Notes

Human. Other species not tested.

Specificity

EXOSC3 (5C3)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for EXOSC3 Antibody (5C3)

Western Blot: EXOSC3 Antibody (5C3) [H00051010-M03]

Western Blot: EXOSC3 Antibody (5C3) [H00051010-M03]

Western Blot: EXOSC3 Antibody (5C3) [H00051010-M03] - Analysis of EXOSC3 expression in Hela S3 NE (Cat # L013V3).
Immunohistochemistry-Paraffin: EXOSC3 Antibody (5C3) [H00051010-M03]

Immunohistochemistry-Paraffin: EXOSC3 Antibody (5C3) [H00051010-M03]

Immunohistochemistry-Paraffin: EXOSC3 Antibody (5C3) [H00051010-M03] - Analysis of monoclonal antibody to EXOSC3 on formalin-fixed paraffin-embedded human kidney. Antibody concentration 3 ug/ml
Western Blot: EXOSC3 Antibody (5C3) [H00051010-M03]

Western Blot: EXOSC3 Antibody (5C3) [H00051010-M03]

Western Blot: EXOSC3 Antibody (5C3) [H00051010-M03] - Analysis of EXOSC3 expression in transfected 293T cell line by EXOSC3 monoclonal antibody (M03), clone 5C3. Lane 1: EXOSC3 transfected lysate (Predicted MW: 29.6 KDa). Lane 2: Non-transfected lysate.
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Applications for EXOSC3 Antibody (5C3)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: EXOSC3

EXOSC3 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Ha

Alternate Names

bA3J10.7, CGI-102, exosome complex exonuclease RRP40, exosome component 3MGC15120, exosome component Rrp40, hRrp-40, hRrp40p, p10Rrp40p, Ribosomal RNA-processing protein 40, RP11-3J10.8, RRP40MGC723

Entrez Gene IDs

51010 (Human)

Gene Symbol

EXOSC3

OMIM

606489 (Human)

UniProt

AAH02437 (Human)

Additional EXOSC3 Products

Product Documents for EXOSC3 Antibody (5C3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for EXOSC3 Antibody (5C3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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