EXOSC3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16392

Novus Biologicals, part of Bio-Techne
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NBP2-16392
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all EXOSC3 Antibodies »

Product Summary for EXOSC3 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human EXOSC3. The exact sequence is proprietary.

Localization

Cytoplasm; Nucleus; nucleolus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

30 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for EXOSC3 Antibody

Western Blot: EXOSC3 Antibody [NBP2-16392]

Western Blot: EXOSC3 Antibody [NBP2-16392]

Western Blot: EXOSC3 Antibody [NBP2-16392] - Sample (30 ug of whole cell lysate) A: A431 B: JurKat C: Raji 12% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: EXOSC3 Antibody [NBP2-16392]

Immunocytochemistry/ Immunofluorescence: EXOSC3 Antibody [NBP2-16392]

Immunocytochemistry/Immunofluorescence: EXOSC3 Antibody [NBP2-16392] - Confocal immunofluorescence analysis of paraformaldehyde-fixed HeLa, using EXOSC3 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are labeled with Alpha-tubulin antibody (Red) at 1:2000.
Immunohistochemistry-Paraffin: EXOSC3 Antibody [NBP2-16392]

Immunohistochemistry-Paraffin: EXOSC3 Antibody [NBP2-16392]

Immunohistochemistry-Paraffin: EXOSC3 Antibody [NBP2-16392] - HeLa xenograft. EXOSC3 antibody dilution: 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Applications for EXOSC3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: EXOSC3

EXOSC3 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Ha

Alternate Names

bA3J10.7, CGI-102, exosome complex exonuclease RRP40, exosome component 3MGC15120, exosome component Rrp40, hRrp-40, hRrp40p, p10Rrp40p, Ribosomal RNA-processing protein 40, RP11-3J10.8, RRP40MGC723

Gene Symbol

EXOSC3

UniProt

Q9NQT5 (Human)

Additional EXOSC3 Products

Product Documents for EXOSC3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for EXOSC3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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