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Exportin 4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56495

Novus Biologicals, part of Bio-Techne
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NB100-56495SS
NB100-56495

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Canine, Chicken, Primate

Cited:

Human, Mouse

Predicted:

Bovine (94%), Xenopus (94%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

A portion of amino acids 850-950 of human Exportin-4 was used as the immunogen.

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in human (isoforms CRA_a, _b, _c), rhesus monkey, chimp (isoforms 1-6), 94% homologous in bovine and xenopus, and 88% homologous in zebrafish.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Exportin 4 Antibody

Western Blot: Exportin 4 Antibody [NB100-56495]

Western Blot: Exportin 4 Antibody [NB100-56495]

Western Blot: Exportin 4 Antibody [NB100-56495] - Analysis of Exportin-4 in Jurkat cell lysate in the 1) absence and 2) presence of immunizing peptide using this antibody.
Immunohistochemistry-Paraffin: Exportin 4 Antibody [NB100-56495]

Immunohistochemistry-Paraffin: Exportin 4 Antibody [NB100-56495]

Immunohistochemistry-Paraffin: Exportin 4 Antibody [NB100-56495] - Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with TEM8 antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Immunohistochemistry-Paraffin: Exportin 4 Antibody [NB100-56495]

Immunohistochemistry-Paraffin: Exportin 4 Antibody [NB100-56495]

Immunohistochemistry-Paraffin: Exportin 4 Antibody [NB100-56495] - Formalin-fixed, paraffin-embedded human liver stained with TEM8 antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.

Applications for Exportin 4 Antibody

Application
Recommended Usage

Western Blot

1-3 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.2% gelatin

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Exportin 4

Nuclear transport receptors of karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-4 is a novel mammalian member of this family. It is a RanGTP-binding protein consisting of N-terminal RanGTP-binding motif. It functions as a nuclear export receptor for eIF-5A and also might function as an export adapter in RNA export. It is also involved in nuclear export of Smad3 and regulation of Smad signaling.

Alternate Names

Exp4, exportin 4, exportin-4, KIAA1721FLJ13046

Entrez Gene IDs

290280 (Rat)

Gene Symbol

XPO4

UniProt

Additional Exportin 4 Products

Product Documents for Exportin 4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Exportin 4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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