FAIM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48764

Novus Biologicals, part of Bio-Techne
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NBP2-48764
NBP2-48764-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FAIM Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MLLPFIRTLPLLCYNHLLVSPDSATLSPPYSLEKMTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FAIM1 Antibody

Immunocytochemistry/ Immunofluorescence: FAIM1 Antibody [NBP2-48764]

Immunocytochemistry/ Immunofluorescence: FAIM1 Antibody [NBP2-48764]

Immunocytochemistry/Immunofluorescence: FAIM1 Antibody [NBP2-48764] - Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.
Immunohistochemistry-Paraffin: FAIM1 Antibody [NBP2-48764]

Immunohistochemistry-Paraffin: FAIM1 Antibody [NBP2-48764]

Immunohistochemistry-Paraffin: FAIM1 Antibody [NBP2-48764] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Applications for FAIM1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FAIM

FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas-mediated apoptosis of B and non-B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology.

Long Name

Fas Apoptotic Inhibitory Molecule 1

Alternate Names

FAIM1, FAIM2, LFG, NMP35

Gene Symbol

FAIM

Additional FAIM Products

Product Documents for FAIM1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FAIM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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