FAIM3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86924

Novus Biologicals, part of Bio-Techne
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NBP1-86924
NBP1-86924-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Fc mu R/FAIM3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RGKTQKVTLNVHSEYEPSWEEQPMPETPKWFHLPYLFQMPAYASSSKFVTRVTTPAQRGKVPPVHHSSPTTQITHRPRVSRASSVAGDKPRTFLPSTTASKISALEGLLKPQTPSYNHHTRLHRQRALDYGSQSGRE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FAIM3 Antibody

Western Blot: FAIM3 Antibody [NBP1-86924]

Western Blot: FAIM3 Antibody [NBP1-86924]

Western Blot: FAIM3 Antibody [NBP1-86924] - Analysis in control (vector only transfected HEK293T lysate) and FAIM3 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: FAIM3 Antibody [NBP1-86924]

Immunocytochemistry/ Immunofluorescence: FAIM3 Antibody [NBP1-86924]

Immunocytochemistry/Immunofluorescence: FAIM3 Antibody [NBP1-86924] - Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol & focal adhesion sites.
Immunohistochemistry-Paraffin: FAIM3 Antibody [NBP1-86924]

Immunohistochemistry-Paraffin: FAIM3 Antibody [NBP1-86924]

Immunohistochemistry-Paraffin: FAIM3 Antibody [NBP1-86924] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.

Applications for FAIM3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Fc mu R/FAIM3

FAIM3 may play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Long Name

Fc mu Receptor

Alternate Names

FAIM3, FCMR, Toso

Gene Symbol

FCMR

Additional Fc mu R/FAIM3 Products

Product Documents for FAIM3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FAIM3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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