FAM98B Antibody

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475]

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human cerebral cortex, colon, lymph node and testis using Anti-FAM98B antibody NBP1-83475 (A) shows similar protein distribution across tissues to independent antibody NBP1-83474 (B).

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475]

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human colon.

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475]

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human lymph node.

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475]

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human testis.

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475]

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human cerebral cortex.

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475]

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human cerebral cortex shows strong nuclear positivity in neuronal cells.

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475]

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human cerebral cortex, gastrointestinal, skeletal muscle and testis using Anti-FAM98B antibody NBP1-83475 (A) shows similar protein distribution across tissues to independent antibody NBP1-83474 (B).

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475]

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human colon shows strong nuclear positivity in glandular cells.

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475]

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human parathyroid gland shows strong nuclear positivity in glandular cells.

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475]

Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human skeletal muscle shows strong nuclear positivity in myocytes.

Western Blot: FAM98B Antibody [NBP1-83475] -

Western Blot: FAM98B Antibody [NBP1-83475] - RTCB is required for induction of XBP1s during plasma cell differentiationB220+ splenocytes of control (Rtcbfl/fl or Rtcbfl/+), Rtcbfl/+Cd23-Cre or Rtcbfl/flCd23-Cre mice were stimulated with 20 μg/ml LPS for 4 days.A, B Protein levels of RTCB, tRNA ligase complex members (DDX1, FAM98B, CGI-99) & XBP1 were monitored by Western blot analysis (n > 3).C FACS-sorted CD138+ CD22− plasmablasts or CD138− CD22low pre-plasmablasts were probed for expression of the indicated proteins by Western blot analysis (n = 2).D Relative mRNA levels of Rtcb, Xbp1s, total Xbp1, Edem1, μM & μS were analyzed by RT–qPCR in fractionated LPS-stimulated cells at day 4 (n = 4, mean expression levels & SEM are displayed). Expression levels were normalized to Actb mRNA levels & to B cells from control mice. An unpaired Student's t-test was used to analyze the statistical significance of differences in mRNA levels (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001). Image collected & cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25378478), licensed under a CC-BY license. Not internally tested by Novus Biologicals.