FBXL7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-55053

Novus Biologicals, part of Bio-Techne
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NBP1-55053
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all FBXL7 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to FBXL7(F-box and leucine-rich repeat protein 7) The peptide sequence was selected from the N terminal of FBXL7. Peptide sequence IRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWD. The peptide sequence for this immunogen was taken from within the described region.

Reactivity Notes

Mouse reactivity reported in multiple pieces of scientific literature.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for FBXL7 Antibody

Western Blot: FBXL7 Antibody [NBP1-55053]

Western Blot: FBXL7 Antibody [NBP1-55053]

Western Blot: FBXL7 Antibody [NBP1-55053] - Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0 ug/ml
Immunohistochemistry: FBXL7 Antibody [NBP1-55053]

Immunohistochemistry: FBXL7 Antibody [NBP1-55053]

Immunohistochemistry: FBXL7 Antibody [NBP1-55053] - Human kidney
Western Blot: FBXL7 Antibody [NBP1-55053]

Western Blot: FBXL7 Antibody [NBP1-55053]

Western Blot: FBXL7 Antibody [NBP1-55053] - Reccomended Titration: 1.25 ug/ml Positive Control: HepG2 cell lysate

Applications for FBXL7 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml
Application Notes
Use in Immunoprecipitation reported in scientific literature (PMID 25654763).

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FBXL7

FBXL7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.

Alternate Names

FBL7FBL6F-box protein Fbl7, F-box and leucine-rich repeat protein 7F-box protein FBL6/FBL7, F-box/LRR-repeat protein 7, KIAA0840

Gene Symbol

FBXL7

UniProt

Q9UJT9 (Human)

Additional FBXL7 Products

Product Documents for FBXL7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FBXL7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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