FBXO42 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84711

Novus Biologicals, part of Bio-Techne
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NBP1-84711
NBP1-84711-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (99%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FBXO42 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: HSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKY

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FBXO42 Antibody

Immunocytochemistry/ Immunofluorescence: FBXO42 Antibody [NBP1-84711]

Immunocytochemistry/ Immunofluorescence: FBXO42 Antibody [NBP1-84711]

Immunocytochemistry/Immunofluorescence: FBXO42 Antibody [NBP1-84711] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: FBXO42 Antibody [NBP1-84711]

Immunohistochemistry-Paraffin: FBXO42 Antibody [NBP1-84711]

Immunohistochemistry-Paraffin: FBXO42 Antibody [NBP1-84711] - Staining of human pancreas shows weak cytoplasmic positivity in exocrine glandular cells.
Immunohistochemistry-Paraffin: FBXO42 Antibody [NBP1-84711]

Immunohistochemistry-Paraffin: FBXO42 Antibody [NBP1-84711]

Immunohistochemistry-Paraffin: FBXO42 Antibody [NBP1-84711] - staining of human prostate shows moderate cytoplasmic positivity in smooth muscle cells.
View 2 more images

Applications for FBXO42 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FBXO42

F-box only protein 42 (FBXO42) is a substrate recognition component of the SKP1-CUL1-F-box protein (SCF) type E3 ubiquitin ligase complex. The FBXO42 protein recognizes p53/TP53; which promotes its ubiquitination and degradation. FBXO42 is a member of the F-box protein family. Members of this family are characterized by an approximately 40-amino acid F-box motif. F-box proteins are also known to interact with SKP1 and other ubiquitination targets through their interaction domains.

Alternate Names

F-box only protein 42, F-box protein 42, Fbx42, JFK, Just one F-box and Kelch domain-containing protein, KIAA1332FBX42

Gene Symbol

FBXO42

Additional FBXO42 Products

Product Documents for FBXO42 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FBXO42 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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