Fc epsilon RI Antibody (9E1)

Novus Biologicals, part of Bio-Techne | Catalog # NB100-63269

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NB100-63269
NB100-63269-0.025mg
Print Quote
Bulk Order
Conjugate
Catalog #
Alexa Fluor 350
NB100-63269AF350
View Product
Alexa Fluor 405
NB100-63269AF405
View Product
Alexa Fluor 488
NB100-63269AF488
View Product
Alexa Fluor 532
NB100-63269AF532
View Product
Alexa Fluor 594
NB100-63269AF594
View Product
Alexa Fluor 647
NB100-63269AF647
View Product
Alexa Fluor 700
NB100-63269AF700
View Product
Alexa Fluor 750
NB100-63269AF750
View Product
Allophycocyanin
NB100-63269APC
View Product
Allophycocyanin/Cy7
NB100-63269APCCY7
View Product
Biotin
NB100-63269B
View Product
CoraFluor 1
NB100-63269CL1
View Product
DyLight 350
NB100-63269UV
View Product
DyLight 405
NB100-63269V
View Product
DyLight 488
NB100-63269G
View Product
DyLight 550
NB100-63269R
View Product
DyLight 594
NB100-63269DL594
View Product
DyLight 650
NB100-63269C
View Product
DyLight 680
NB100-63269FR
View Product
DyLight 755
NB100-63269IR
View Product
FITC
NB100-63269F
View Product
HRP
NB100-63269H
View Product
Janelia Fluor 525
NB100-63269JF525
View Product
Janelia Fluor 549
NB100-63269JF549
View Product
Janelia Fluor 585
NB100-63269JF585
View Product
Janelia Fluor 635
NB100-63269JF635
View Product
Janelia Fluor 646
NB100-63269JF646
View Product
Janelia Fluor 669
NB100-63269JF669
View Product
mFluor Violet 450 SE
NB100-63269MFV450
View Product
mFluor Violet 500 SE
NB100-63269MFV500
View Product
mFluor Violet 610 SE
NB100-63269MFV610
View Product
PE
NB100-63269PE
View Product
PE/Atto594
NB100-63269PEATT594
View Product
PE/Cy5.5
NB100-63269PECY55
View Product
PE/Cy7
NB100-63269PECY7
View Product
PerCP
NB100-63269PCP
View Product
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 9E1

Concentration

1.0 mg/ml

View all Fc epsilon RI Antibodies »

Product Summary for Fc epsilon RI Antibody (9E1)

Immunogen

Made to Human Fc EPSILON R1 ALPHA

Localization

Membrane; single pass type I membrane protein.

Specificity

NB100-63269 recognizes the human high affinity Fc receptor for IgE (Fc epsilon R1), which plays a central role in the IgE-mediated allergic response. Fc epsilon R1 consists of four subunits, a high affinity IgE binding alpha subunit, a beta chain and two di-sulphide linked gamma subunits. Clone 9E1 specifically recognizes the extracellular D1 domain of the Fc epsilon R1 alpha chain. Fc epsilon R1 is primarily expressed on mast cells and basophils but expression of Fc epsilon R1 has also been reported on monocytes, Langerhans cells and dendritic cells from patients with atopic diseases.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Fc epsilon RI Antibody (9E1)

Flow Cytometry: Fc epsilon RI Antibody (9E1) - BSA Free [NB100-63269]

Flow Cytometry: Fc epsilon RI Antibody (9E1) - BSA Free [NB100-63269]

Flow Cytometry: Fc epsilon RI Antibody (9E1) [NB100-63269] - Staining of human peripheral blood cells with Mouse anti Human Fc epsilon RI PE showing staining of eosinophils.
Flow Cytometry: Fc epsilon RI Antibody (9E1) - BSA Free [NB100-63269]

Flow Cytometry: Fc epsilon RI Antibody (9E1) - BSA Free [NB100-63269]

Flow Cytometry: Fc epsilon RI Antibody (9E1) [NB100-63269] - Staining of human peripheral blood cells with MOUSE ANTI HUMAN FC EPSILON R1 showing staining of eosinophils.

Applications for Fc epsilon RI Antibody (9E1)

Application
Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

1:50-1:100

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Fc epsilon RI

The allergic reaction is mediated through the IgE high affinity receptor (FceRI). When a multivalent antigen is presented, a redistribution of the monomeric IgE FceRI receptor complexes cause the degranulation of mast cells and basophils, resulting in the subsequent release of factors responsible for the allergic reaction. The FceRI receptor is a tetrameric complex, consisting of a a-chain, b-chain and a dimeric g-chain. While the a-chain is primarily involved with the binding of IgE, the signal is transferred through the g subunit, which contains the immunoreceptor tyrosine activation motifs (ITAM) critical for initiating receptor mediated signal transduction through the Syk and Lyn tyrosine kinases. The FceRI receptor is able to engage and disengage the IgE, providing a versatile model for studying the function of kinase coupled receptors.

Alternate Names

alpha polypeptide, Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, Fc-epsilon RI-alpha, FcERI, high affinity immunoglobulin epsilon receptor alpha-subunit, high affinity immunoglobulin epsilon receptor subunit alpha, high-affinity, of mast cells, alpha polypeptide

Gene Symbol

FCER1A

UniProt

P12319

Additional Fc epsilon RI Products

Product Documents for Fc epsilon RI Antibody (9E1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Fc epsilon RI Antibody (9E1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.