Fc gamma RIIA/CD32a Antibody (3B6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26587

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26587-100ul
NBP3-26587-50ul
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 3B6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Fc gamma RIIA/CD32a Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from Human Fc gamma RIIA/CD32a [UniProt P12318]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Fc gamma RIIA/CD32a Antibody (3B6)

Fc gamma RIIA/CD32a Antibody (3B6)

Western Blot: Fc gamma RIIA/CD32a Antibody (3B6) [NBP3-26587] -

Western Blot: Fc gamma RIIA/CD32a Antibody (3B6) [NBP3-26587] - Positive Western Blot detected in: THP-1 whole cell lysate.
All lanes: Fc gamma RIIA/CD32a Antibody at 1: 1000
Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.
Predicted band size: 35, 36 kDa
Observed band size: 45 kDa

Applications for Fc gamma RIIA/CD32a Antibody (3B6)

Application
Recommended Usage

Western Blot

1:500-1:5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Fc gamma RIIA/CD32a

The FCGR2A gene encodes a low affinity immunoglobulin gamma Fc region receptor II-a protein that in isoform 1 is 317 amino acids long at 35 kDA and at isoform 2 is 316 amino acids long at nearly 35 kDA. These proteins are found on the surface of many immune system response cells that act as a low affinity receptor through encouraging responses against pathogens and soluble antigens. Additionally, it functions to initiate phagocytosis of opsonized antigens. FCGR2A participates in Fc-GammaR pathway, osteoclast differentiation, signaling events controlled by PTP1B, and NFAT in immune response. It is known to interact with genes SYK, FYN, HCK, LGALS3, and PIK3R1. FCGR2A is linked to lupus, thrombocytopenia, b-cell lymphomas, otitis media, adult-onset still's disease, guillain-barre syndrome, asymptomatic dengue, severe acute respiratory syndrome.

Long Name

Fc gamma Receptor II A

Alternate Names

CD32a, FCGR2A, FcgRIIA, FCRIIA

Gene Symbol

FCGR2A

Additional Fc gamma RIIA/CD32a Products

Product Documents for Fc gamma RIIA/CD32a Antibody (3B6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Fc gamma RIIA/CD32a Antibody (3B6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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