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FCAR/CD89 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15820

Novus Biologicals, part of Bio-Techne
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NBP2-15820

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human FCAR/CD89. The exact sequence is proprietary.

Localization

Isoform A; 1: Cell membrane; Single-pass type I membrane protein; 2: Cell membrane; Single-pass type I membrane protein; 3: Cell membrane; Single-pass type I membrane protein; Isoform B: Secreted; Isoform B-delta-S2: Secreted

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

32 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FCAR/CD89 Antibody

Western Blot: FCAR/CD89 Antibody [NBP2-15820]

Western Blot: FCAR/CD89 Antibody [NBP2-15820]

Western Blot: CD89 Antibody [NBP2-15820] - Sample (30 ug of whole cell lysate) A: Raji B: K562 5% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: FCAR/CD89 Antibody [NBP2-15820]

Immunohistochemistry-Paraffin: FCAR/CD89 Antibody [NBP2-15820]

Immunohistochemistry-Paraffin: FCAR/CD89 Antibody [NBP2-15820] - Staining at cytoplasm in human cervical carcinoma.

Applications for FCAR/CD89 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FCAR/CD89

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Long Name

IgA Fc Receptor

Alternate Names

CD89

Gene Symbol

FCAR

UniProt

Additional FCAR/CD89 Products

Product Documents for FCAR/CD89 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FCAR/CD89 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.