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FERMT3/URP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20821

Novus Biologicals, part of Bio-Techne
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NBP2-20821

Key Product Details

Species Reactivity

Human, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human FERMT3/URP2. The exact sequence is proprietary.

Localization

Cytoplasm (Probable); Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

76 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FERMT3/URP2 Antibody

Western Blot: FERMT3/URP2 Antibody [NBP2-20821]

Western Blot: FERMT3/URP2 Antibody [NBP2-20821]

Western Blot: URP2 Antibody [NBP2-20821] - Sample (30 ug of whole cell lysate) A: Jurkat B: Raji 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: FERMT3/URP2 Antibody [NBP2-20821]

Immunocytochemistry/ Immunofluorescence: FERMT3/URP2 Antibody [NBP2-20821]

Immunocytochemistry/Immunofluorescence: FERMT3/URP2 Antibody [NBP2-20821] - URP2 antibody detects URP2 protein at cytoplasm by immunofluorescent analysis.Sample: Jurkat cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: URP2 protein stained by URP2 antibody diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.
Immunohistochemistry-Paraffin: FERMT3/URP2 Antibody [NBP2-20821]

Immunohistochemistry-Paraffin: FERMT3/URP2 Antibody [NBP2-20821]

Immunohistochemistry-Paraffin: URP2 Antibody [NBP2-20821] - Immunohistochemical analysis of paraffin-embedded RT2 xenograft, using antibody at 1:500 dilution.

Applications for FERMT3/URP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FERMT3

Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

Long Name

Fermitin Family Member 3

Alternate Names

KIND3, Kindlin 3, MIG2B, UNC112C, URP2, URP2SF

Gene Symbol

FERMT3

UniProt

Additional FERMT3 Products

Product Documents for FERMT3/URP2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FERMT3/URP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.