FEZ1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76395

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all FEZ1 Antibodies »

Product Summary for FEZ1 Antibody - BSA Free

Immunogen

Antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FEZ1. The immunogen is located within amino acids 270 - 320 of FEZ1. Amino Acid Squence: KQKEQRELMKKRRKEKGL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FEZ1 Antibody - BSA Free

Western Blot: FEZ1 AntibodyBSA Free [NBP1-76395]

Western Blot: FEZ1 AntibodyBSA Free [NBP1-76395]

Western Blot: FEZ1 Antibody [NBP1-76395] - Analysis of SAPAP2 in Raji cell lysate with SAPAP2 antibody at (A) 0.5 and (B) 1 ug/mL.
Western Blot: FEZ1 AntibodyBSA Free [NBP1-76395]

Western Blot: FEZ1 AntibodyBSA Free [NBP1-76395]

Western Blot: FEZ1 Antibody [NBP1-76395] - SK-N-SH cell lysate with FEZ1 antibody at 1 ug/mL in the (A) presence and (B) absence of blocking peptide.

Applications for FEZ1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

0.5-1 ug/ml
Application Notes
Despite its predicted molecular weight, FEZ1 will often run at higher molecular weight in SDS-PAGE.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FEZ1

Similar to its C. elegans homolog UNC-76, mammalian FEZ1, an abundant membrane protein and protein kinase C (PKC)-Z substrate, is involved in axonal guidance. Following phosphorylation by PKC-Z, FEZ1 translocates from the plasma membrane to the cytoplasm. FEZ1 is then able to interact with a number of proteins involved in axonal outgrowth and cellular transport such as DISC1, a candidate gene for schizophrenia, as well as kinesin-1, a microtubule-based motor protein. FEZ1 also interacts with proteins involved in transcriptional regulation and chromatin remodeling, suggesting that FEZ1 may have nuclear regulatory functions in addition to those for neuronal development. At least two distinct isoforms of FEZ1 are known to exist. Despite its predicted molecular weight, FEZ1 will often run at higher molecular weight in SDS-PAGE.

Alternate Names

fasciculation and elongation protein zeta 1 (zygin I), fasciculation and elongation protein zeta-1, Zygin I, Zygin-1

Gene Symbol

FEZ1

UniProt

Q99689 (Human)

Additional FEZ1 Products

Product Documents for FEZ1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FEZ1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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