Fibrinogen gamma chain Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21374

Novus Biologicals, part of Bio-Techne
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NBP3-21374-100ul
NBP3-21374-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Fibrinogen gamma chain Antibodies »

Product Summary for Fibrinogen gamma chain Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Fibrinogen gamma chain Antibody

Immunocytochemistry/Immunofluorescence: Fibrinogen gamma chain Antibody [NBP3-21374] -

Immunocytochemistry/Immunofluorescence: Fibrinogen gamma chain Antibody [NBP3-21374] -

Staining of human cell line Hep G2 shows localization to endoplasmic reticulum.
Western Blot: Fibrinogen gamma chain Antibody [NBP3-21374] -

Western Blot: Fibrinogen gamma chain Antibody [NBP3-21374] -

Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10 | Lane 2: RT4 | Lane 3: U-251 MG | Lane 4: Human Plasma | Lane 5: Liver | Lane 6: Tonsil

Applications for Fibrinogen gamma chain Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Fibrinogen gamma chain

The protein encoded by the Fibrinogen gamma chain gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Alternate Names

fibrinogen gamma chain, fibrinogen, gamma polypeptide

Gene Symbol

FGG

Additional Fibrinogen gamma chain Products

Product Documents for Fibrinogen gamma chain Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Fibrinogen gamma chain Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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