FKBP13/FKBP2 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-97373
Key Product Details
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Description
Scientific Data Images for FKBP13/FKBP2 Antibody
Immunohistochemistry-Paraffin: FKBP13/FKBP2 Antibody [NBP2-97373]
Immunohistochemistry-Paraffin: FKBP13/FKBP2 Antibody [NBP2-97373] - Immunochemical staining of human FKBP13/FKBP2 in human epididymis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.Applications for FKBP13/FKBP2 Antibody
Immunohistochemistry-Paraffin
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Background: FKBP13
FK506 binding protein, 13 kilodalton molecular weight (FKBP13), also called FKBP2, is a peptidyl-prolyl isomerase that catalyzes the transition between cis- and trans-proline residues critical for proper folding of proteins. The immunosuppressants FK506 and rapamycin are potent inhibitors of FKBP13. This isomerase is localized in the endoplasmic reticulum and is also associated with cytoskeletal elements such as erythrocyte band 4.1. FKBP13 levels are increased by treatments that affect golgi protein processing such as tunicamycin and heat shock, suggesting that FKBP13 is important in the unfolded protein response observed with endoplasmic reticulum stress.
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Additional FKBP13 Products
Product Specific Notices for FKBP13/FKBP2 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.