Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all FKBP15 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human FKBP15. The immunogen is located within amino acids 30 - 80 of FKBP15. Amino Acid Squence: YTAPKQPKKGQGTAATG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FKBP15 Antibody - BSA Free

Western Blot: FKBP15 AntibodyBSA Free [NBP1-77352]

Western Blot: FKBP15 AntibodyBSA Free [NBP1-77352]

Western Blot: FKBP15 Antibody [NBP1-77352] - 3T3 cell lysate with FKBP15 antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: FKBP15 Antibody - BSA Free [NBP1-77352]

Immunocytochemistry/ Immunofluorescence: FKBP15 Antibody - BSA Free [NBP1-77352]

Immunocytochemistry/Immunofluorescence: FKBP15 Antibody [NBP1-77352] - Immunofluorescence of FKBP15 in mouse brain tissue with FKBP15 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: FKBP15 Antibody - BSA Free [NBP1-77352]

Immunohistochemistry-Paraffin: FKBP15 Antibody - BSA Free [NBP1-77352]

Immunohistochemistry-Paraffin: FKBP15 Antibody [NBP1-77352] - Mouse brain tissue with FKBP15 antibody at 2.5 ug/ml.
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Applications for FKBP15 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FKBP15

FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons; overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.

Alternate Names

FK506 binding protein 15, 133kDa, FK506-binding protein 133kDa, FK506-binding protein 15, FKBP133, FKBP-133, FKBP-15,133 kDa FKBP, PPP1R76,133 kDa FK506-binding protein, regulatory subunit 76, WAFL

Gene Symbol

FKBP15

UniProt

NP_056073 (Human)

Additional FKBP15 Products

Product Documents for FKBP15 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FKBP15 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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