FKBP51/FKBP5 Antibody (OTI3E9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-47755

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI3E9

Concentration

1 mg/ml

View all FKBP51 Antibodies »

Product Specifications

Immunogen

Full-length protein expressed in 293T cell transfected with human FKBP5 expression vector

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Specificity

This antibody is specific for Homo sapiens FK506 binding protein 5 (FKBP5), transcript variant 1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

51.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FKBP51/FKBP5 Antibody (OTI3E9)

Western Blot: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Western Blot: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Western Blot: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FKBP5/FKBP51 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FKBP5/FKBP51.
Immunocytochemistry/Immunofluorescence: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] Staining of COS7 cells transiently transfected by pCMV6-ENTRY FKBP5/FKBP51.
Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded prostate tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.
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Applications for FKBP51/FKBP5 Antibody (OTI3E9)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:50

Immunohistochemistry-Paraffin

1:50

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FKBP51

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition.It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Long Name

51 kDa FK506 Binding Protein

Alternate Names

Dit1, FKBP5, FKBP54, Ptg-10

Entrez Gene IDs

2289 (Human)

Gene Symbol

FKBP5

Additional FKBP51 Products

Product Documents for FKBP51/FKBP5 Antibody (OTI3E9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FKBP51/FKBP5 Antibody (OTI3E9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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