FKTN Antibody (7J5N6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15472

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15472-100ul
NBP3-15472-20ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 7J5N6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all FKTN Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 362-461 of human FKTN (O75072). DVKLDVFFFYEETDHMWNGGTQAKTGKKFKYLFPKFTLCWTEFVDMKVHVPCETLEYIEANYGKTWKIPVKTWDWKRSPPNVQPNGIWPISEWDEVIQLY

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FKTN Antibody (7J5N6)

Western Blot: FKTN Antibody (7J5N6) [NBP3-15472]

Western Blot: FKTN Antibody (7J5N6) [NBP3-15472]

Western Blot: FKTN Antibody (7J5N6) [NBP3-15472] - Western blot analysis of extracts of various cell lines, using FKTN antibody (NBP3-15472) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Immunohistochemistry-Paraffin: FKTN Antibody (7J5N6) [NBP3-15472]

Immunohistochemistry-Paraffin: FKTN Antibody (7J5N6) [NBP3-15472]

Immunohistochemistry-Paraffin: FKTN Antibody (7J5N6) [NBP3-15472] - Immunohistochemistry of paraffin-embedded human colon using FKTN Rabbit mAb (NBP3-15472) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Applications for FKTN Antibody (7J5N6)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FKTN

FKTN genes encode fukutin proteins that in isoform 1 are 461 amino acids long at 54 kDA and at isoform 2 are 430 amino acids long at 49 kDA. These proteins are thought to participate in glycosylation of alpha-dystroglycan/DAG1 as it is probably a glycosyltransferase. Additionally, it may reinforce large a complex surrounding the outside and inside of muscle membranes, further enhancing brain development. FKTN is involved with the CNBP gene. Defects in this gene cause myscular dystrophy-dystroglycanopathy congenital types A4, B4, C4, and cadiomyopathy dilated type 1X. FKTN is also linked to optic atrophy, cleft lip, walker-warburg syndrome, dubowitz syndrome, retinal detachment, and neuronal migration disorders.

Alternate Names

CMD1X, EC 2.-, FCMDMGC134945, fukutin, Fukuyama type congenital muscular dystrophy (fukutin), Fukuyama type congenital muscular dystrophy protein, Fukuyama-type congenital muscular dystrophy protein, LGMD2MMGC134944, MDDGA4, MDDGB4, MDDGC4, MGC126857, MGC138243

Gene Symbol

FKTN

Additional FKTN Products

Product Documents for FKTN Antibody (7J5N6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FKTN Antibody (7J5N6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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