Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunoprecipitation, Microarray, Western Blot

Cited:

Microarray, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all FNBP1 Antibodies »

Product Specifications

Immunogen

The immunogen for this product maps to a region between residue 350 and 400 of human Formin-Binding Protein 17 using the numbering given in entry NP_055848.1 (GeneID 23048).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FNBP1 Antibody

Western Blot: FNBP1 Antibody [NBP1-47260]

Western Blot: FNBP1 Antibody [NBP1-47260]

Western Blot: FNBP1 Antibody [NBP1-47260] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-FBP17 antibody NBP1-47260 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 10 ug/mg lysate. FBP17 was also immunoprecipitated by rabbit anti-FBP17 antibody NBP1-47261, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

Applications for FNBP1 Antibody

Application
Recommended Usage

Immunoprecipitation

5-15 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
Use in MiAr reported in secitific publication PMID: 32665637

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: FNBP1

The protein recognised by this antibody is a member of the formin binding protein family. The protein contains an N terminal Fer/Cdc42 interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled coil domain, a proline rich motif, a second coiled coil domain, a Rho family protein binding domain (RBD), and a C terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human.

Alternate Names

FBP17KIAA0554Formin-binding protein 17, formin binding protein 1, formin-binding protein 1, hFBP17, MGC126804

Entrez Gene IDs

23048 (Human)

Gene Symbol

FNBP1

Additional FNBP1 Products

Product Documents for FNBP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FNBP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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