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Follistatin-like 4/FSTL4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-91913

Novus Biologicals, part of Bio-Techne
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NBP1-91913
NBP1-91913-25ul

Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: WMDPGTSRGPDVGVGESQAEEPRSFEVTRREGLSSHNELLASCGKKFCSRGSRCVLSRKTGEPECQCLEACRPSYVPVCGS

Reactivity Notes

Rat reactivity reported in scientific literature (VanderWall K et al).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Follistatin-like 4/FSTL4 Antibody

Immunohistochemistry-Paraffin: Follistatin-like 4/FSTL4 Antibody [NBP1-91913]

Immunohistochemistry-Paraffin: Follistatin-like 4/FSTL4 Antibody [NBP1-91913]

Immunohistochemistry-Paraffin: Follistatin-like 4/FSTL4 Antibody [NBP1-91913] - Staining of human rectum shows strong granular cytoplasmic positivity in glandular cells with distinct extracellular material.

Applications for Follistatin-like 4/FSTL4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Follistatin-like 4/FSTL4

FSTL4 (Follistatin-like protein 4; also FSL4, SPIG1 and D/Bsp120I-1) is a likely secreted, 90 kDa (predicted) member of the follistatin gene family of TGF-beta superfamily inhibitors. It is widely expressed, being found in neurons (retinal ganglion and cerebellar Purkinje cells), cardiac muscle cells, smooth muscle cells and intestinal epithelium. Mature mouse FSTL4 is 819 amino acids (aa) in length (aa 23-841). It contains one kazal-like domain (aa 80-134), an EF-hand motif (aa 173-208), and two Ig-like domains (aa 250-336 and 340-425). There are two potential splice forms, one that shows an alternative start site at Met315, and a second that possesses a His residue substitution for aa 518-841. Full-length mature mouse FSTL4 shares 95% and 84% aa identity with rat and human FSTL4, respectively.

Alternate Names

Follistatin like 4, FSL4, FSTL4

Gene Symbol

FSTL4

Additional Follistatin-like 4/FSTL4 Products

Product Documents for Follistatin-like 4/FSTL4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Follistatin-like 4/FSTL4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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