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FOLR2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-43654

Novus Biologicals, part of Bio-Techne
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NBP2-43654

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Chinese Hamster

Predicted:

Rhesus Macaque (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Folate receptor beta. The exact sequence is proprietary.

Reactivity Notes

Rat (84%), Bovine (86%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FOLR2 Antibody

Immunocytochemistry/Immunofluorescence: FOLR2 Antibody [NBP2-43654] -

Immunocytochemistry/Immunofluorescence: FOLR2 Antibody [NBP2-43654] - FOLR2 antibody detects FOLR2 protein at endoplasmic reticulum by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: FOLR2 stained by FOLR2 antibody diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody diluted at 1:1000. Blue: Fluoroshield with DAPI. Scale bar= 10um.
FOLR2 Antibody

Immunohistochemistry-Paraffin: FOLR2 Antibody [NBP2-43654] -

Immunohistochemistry-Paraffin: FOLR2 Antibody [NBP2-43654] - FOLR2 antibody detects FOLR2 protein at cell membrane and secreted by immunohistochemical analysis. Sample: Paraffin-embedded human hepatocellular carcinoma. FOLR2 stained by FOLR2 antibody (NBP2-43654) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
FOLR2 Antibody

Western Blot: FOLR2 Antibody [NBP2-43654] -

Western Blot: FOLR2 Antibody [NBP2-43654] - Human synovial fluid (50 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with FOLR2 antibody (NBP2-43654) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for FOLR2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Assay dependent

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FOLR2

Folate Receptor 2 (FOLR2), also known as Folate Receptor beta, is a 38 kDa glycoprotein that is anchored to the membrane via glycosyl phosphatidylinositol. It mediates the cellular uptake of dietary folates that are required for key steps in amino acid metabolism. FOLR2 is predominantly expressed in placenta, myeloid cells, and some CD34+ hematopoietic progenitor cells. It is upregulated on some cancer cells and at sites of chronic inflammation.

Long Name

Folate Receptor 2

Alternate Names

beta-HFR, FR-beta, FR-P3

Gene Symbol

FOLR2

Additional FOLR2 Products

Product Documents for FOLR2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FOLR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.