FosB/G0S3 Antibody (83B1138) - Azide Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33219

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 83B1138

Format

Azide Free

Concentration

0.5 mg/ml

View all FosB/G0S3 Antibodies »

Product Specifications

Immunogen

This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 2-15 of human FosB.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for FosB/G0S3 Antibody (83B1138) - Azide Free

Western Blot: FosB/G0S3 Antibody (83B1138)Azide Free [NBP2-33219]

Western Blot: FosB/G0S3 Antibody (83B1138)Azide Free [NBP2-33219]

Western Blot: FosB/G0S3 Antibody (83B1138) - Azide Free [NBP2-33219] - Analysis of FosB in HeLa cell lysate where bands are observed at ~38 kDa representing FosB and at ~35 kDa representing delta FosB. Image from the standard format of this antibody.

Applications for FosB/G0S3 Antibody (83B1138) - Azide Free

Application
Recommended Usage

Western Blot

2 ug/ml
Application Notes
In HeLa, a 46 kDa band is observed.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS - BSA free

Format

Azide Free

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FosB/G0S3

Fos and Jun dimerize to form Activator Protein-1 (AP-1), a transcriptional factor that binds to the 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE) of several cellular and viral genes including human collagenase, metallothionein IIa, stromelysin, interleukin 2, SV40 and polyoma. Fos and Jun contain the 'leucine-zipper' motif that allows for dimerization and an adjacent basic domain required for biological activity. The functionally active form of Fos is in a heterodimer with a member of the Jun family. While Jun family members can form functional homodimers, studies indicate that Fos family members do not self-associate and therefore do not bind DNA on their own. The various dimers differ in their ability to transactivate AP-1 dependent genes.

Long Name

FBJ Murine Osteosarcoma Viral Oncogene Homolog B

Alternate Names

G0S3

Gene Symbol

FOSB

Additional FosB/G0S3 Products

Product Documents for FosB/G0S3 Antibody (83B1138) - Azide Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FosB/G0S3 Antibody (83B1138) - Azide Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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