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FOX2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05534

Novus Biologicals, part of Bio-Techne
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NBP3-05534-100ul
NBP3-05534-50ul

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Chicken IgY

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

N-terminal 99 amino acids of human FOX2 expressed in and purified from E. coli

Clonality

Polyclonal

Host

Chicken

Isotype

IgY

Scientific Data Images for FOX2 Antibody

Western Blot: FOX2 Antibody [NBP3-05534]

Western Blot: FOX2 Antibody [NBP3-05534]

Western Blot: FOX2 Antibody [NBP3-05534] - Western blot analysis of nuclear enriched fractions from different tissue and cells using FOX2 Antibody in green: [1] protein standard , [2] rat brain, [3] mouse brain, [4] HEK293, and [5] NIH-3T3 cells. The bands between 50kDa and 75kDa correspond to the FOX2 protein.
Immunocytochemistry/ Immunofluorescence: FOX2 Antibody [NBP3-05534]

Immunocytochemistry/ Immunofluorescence: FOX2 Antibody [NBP3-05534]

Immunocytochemistry/Immunofluorescence: FOX2 Antibody [NBP3-05534] - Immunofluorescent analysis of mouse cerebellum section stained with FOX2 Antibody at a dilution of 1:2,000 in red, and costained with mouse mAb to NF-L at a dilution of 1:5,000 in green. The blue is Hoechst staining of nuclear DNA. Following transcardial perfusion of mouse with 4% paraformaldehyde, brain was post fixed for 24 hours, cut to 45 uM, and free-floating sections were stained with above antibodies. FOX2 antibody reveals protein expressed in the nuclei of certain granule cells and all Purkinje cells, while NF-L antibody labels dendrites and axons.
Immunocytochemistry/ Immunofluorescence: FOX2 Antibody [NBP3-05534]

Immunocytochemistry/ Immunofluorescence: FOX2 Antibody [NBP3-05534]

Immunocytochemistry/Immunofluorescence: FOX2 Antibody [NBP3-05534] - Immunofluorescent analysis of mouse cerebellum section stained with FOX2 Antibody at a dilution of 1:2,000 in red, and costained with mouse mAb to NF-L at a dilution of 1:5,000 in green. The blue is Hoechst staining of nuclear DNA. Following transcardial perfusion of mouse with 4% paraformaldehyde, brain was post fixed for 24 hours, cut to 45 uM, and free-floating sections were stained with above antibodies. FOX2 antibody reveals protein expressed in the nuclei of certain granule cells and all Purkinje cells, while NF-L antibody labels dendrites and axons.

Applications for FOX2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:2000

Immunohistochemistry

1:2000

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

IgY purified

Formulation

Supplied as concentrated total IgY preparation from egg yolk. Exact concentration of target specific IgY is not quantifiable as the preparation contains both immune IgY specific for the target and also irrelevant, non-immune IgY.

Preservative

0.035% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: FOX2

FOX2 is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternate Names

dJ106I20.3, Fox-1 homolog B, fox-1 homologue, FOX2Fox-2, fxh, hexaribonucleotide binding protein 2, Hexaribonucleotide-binding protein 2, HRNBP2FOX-2, RBM9RTAHNRBP2, Repressor of tamoxifen transcriptional activity, RNA binding motif protein 9, RNA binding protein fox-1 homolog 2, RNA binding protein, fox-1 homolog (C. elegans) 2, RNA-binding motif protein 9, RNA-binding protein 9

Gene Symbol

RBFOX2

Additional FOX2 Products

Product Documents for FOX2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FOX2 Antibody

Chicken products cannot be exported to Canada.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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