FoxH1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41196

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all FoxH1 Antibodies »

Product Summary for FoxH1 Antibody - BSA Free

Immunogen

Antibody was raised against a 19 amino acid peptide near the amino terminus of human FOXH1. The immunogen is located within the first 50 amino acids of FOXH1. Amino Acid Squence: CQPPKRRKKRYLRHDKPPYT

Specificity

FOXH1 antibody is predicted to not cross-react with any other members of the forkhead box family.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FoxH1 Antibody - BSA Free

Western Blot: FoxH1 AntibodyBSA Free [NBP2-41196]

Western Blot: FoxH1 AntibodyBSA Free [NBP2-41196]

Western Blot: FoxH1 Antibody [NBP2-41196] - Western blot analysis of FOXH1 in human liver tissue lysate with FOXH1 antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: FoxH1 Antibody - BSA Free [NBP2-41196]

Immunocytochemistry/ Immunofluorescence: FoxH1 Antibody - BSA Free [NBP2-41196]

Immunocytochemistry/Immunofluorescence: FoxH1 Antibody [NBP2-41196] - Immunofluorescence of FOXH1 in human liver tissue with FOXH1 antibody at 20 ug/mL.

Applications for FoxH1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FoxH1

Fas, also referred to as CD95 or APO-1, is a type I transmembrane protein that plays a central role mediating viral immunity. TIA-1 and TIAR are two closely related proteins that possess three RRMs (RNA recognition motifs), designated RRM 1, 2 and 3, respectively. Although both TIA-1 and TIAR are thought to function as mediators of apoptotic cell death, their specific roles in such pathways are unknown. Unlike TIA-1, which is found in the granules of cytotoxic lymphocytes, TIAR expression is limited to the nucleus and found in a much broader range of cells including, but not limited to, cells of hematopoietic origin. TIAR is translocated to the cytoplasm shortly after Fas ligation and this event immediately proceeds the onset of DNA fragmentation. A novel serine/ threonine kinase that is activated as a result of Fas ligation, designated FAST (Fas-activated serine/threonine), shows kinase specificity towards both TIA-1 and TIAR. In unstimulated Jurkat cells, FAST resides in the cytoplasm as a highly phosphorylated protein and is quickly dephosphorylated and activated in response to stimulated Fas.

Long Name

Forkhead Box J1

Alternate Names

FAST1

Gene Symbol

FOXH1

Additional FoxH1 Products

Product Documents for FoxH1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FoxH1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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