FPGS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16526

Novus Biologicals, part of Bio-Techne
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NBP2-16526
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FPGS Antibodies »

Product Summary for FPGS Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human FPGS. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine (81%).

Localization

Mitochondrion; Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FPGS Antibody

Western Blot: FPGS Antibody [NBP2-16526]

Western Blot: FPGS Antibody [NBP2-16526]

Western Blot: FPGS Antibody [NBP2-16526] - Analysis of FPGS expression in transfected 293T cell line by FPGS polyclonal antibody. A: Non-transfected lysate. B: FPGS transfected lysate. 7. 5% SDS PAGE gel, diluted at 1:1000.

Applications for FPGS Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FPGS

This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq]

Alternate Names

EC 6.3.2.17, Folylpoly-gamma-glutamate synthetase, folylpolyglutamate synthase, mitochondrial

Gene Symbol

FPGS

UniProt

Q05932 (Human)

Additional FPGS Products

Product Documents for FPGS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FPGS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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