FVT1 Antibody (2B2-3C11)

Novus Biologicals, part of Bio-Techne | Catalog # H00002531-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2B2-3C11

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FVT1 Antibodies »

Product Specifications

Immunogen

FVT1 (AAH08797.1, 12 a.a. ~ 332 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. FVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQREKSENADKTA

Specificity

FVT1 - follicular lymphoma variant translocation 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for FVT1 Antibody (2B2-3C11)

Western Blot: FVT1 Antibody (2B2-3C11) [H00002531-M01]

Western Blot: FVT1 Antibody (2B2-3C11) [H00002531-M01]

Western Blot: FVT1 Antibody (2B2-3C11) [H00002531-M01] - FVT1 monoclonal antibody (M01), clone 2B2-3C11 Analysis of FVT1 expression in Jurkat.
Sandwich ELISA: FVT1 Antibody (2B2-3C11) [H00002531-M01] - Detection limit for recombinant GST tagged FVT1 is approximately 1ng/ml as a capture antibody.

Applications for FVT1 Antibody (2B2-3C11)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FVT1

The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.

Alternate Names

3-ketodihydrosphingosine reductase, DHSR, EC 1.1.1.102,3-dehydrosphinganine reductase, FLJ36555, FLJ92680, follicular lymphoma variant translocation 1, Follicular variant translocation protein 1, FVT-1, FVT1KDS reductase, SDR35C1, short chain dehydrogenase/reductase family 35C, member 1

Entrez Gene IDs

2531 (Human)

Gene Symbol

KDSR

OMIM

136440 (Human)

UniProt

AAH08797 (Human)

Additional FVT1 Products

Product Documents for FVT1 Antibody (2B2-3C11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FVT1 Antibody (2B2-3C11)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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