FXYD5/Dysadherin Antibody (CL14039)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24586

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # CL14039

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FXYD5/Dysadherin Antibodies »

Product Specifications

Immunogen

This antibody was designed to target the recombinant protein FXYD5/Dysadherin, with the precise immunogen sequence being withheld for proprietary reasons.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for FXYD5/Dysadherin Antibody (CL14039)

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14039) [NBP3-24586]

Staining of human tonsil shows moderate membranous positivity in lymphoid cells.

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14039) [NBP3-24586]

Staining of human fallopian tube shows moderate membranous and cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14039) [NBP3-24586]

Staining of human breast cancer shows strong membranous positivity in tumor cells.
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Applications for FXYD5/Dysadherin Antibody (CL14039)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FXYD5/Dysadherin

Dysadherin encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane.

Long Name

FXYD Domain-containing Ion Transport Regulator 5

Alternate Names

DYSAD, Dysadherin, EF-8, IWU1, KCT1, OIT2, PRO6241, RIC

Gene Symbol

FXYD5

Additional FXYD5/Dysadherin Products

Product Documents for FXYD5/Dysadherin Antibody (CL14039)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FXYD5/Dysadherin Antibody (CL14039)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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